Motif ID: HOX{A5,B5}.p2

Z-value: 1.356


Transcription factors associated with HOX{A5,B5}.p2:

Gene SymbolEntrez IDGene Name
HOXA5 3202 homeobox A5
HOXB5 3215 homeobox B5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXA5chr7_-_27149750-0.562.3e-02Click!
HOXB5chr17_-_44026042-0.273.0e-01Click!


Activity profile for motif HOX{A5,B5}.p2.

activity profile for motif HOX{A5,B5}.p2


Sorted Z-values histogram for motif HOX{A5,B5}.p2

Sorted Z-values for motif HOX{A5,B5}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A5,B5}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_196874867 2.547 PTPRC
protein tyrosine phosphatase, receptor type, C
chr7_+_5289079 2.482 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr6_+_33495824 2.360 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr17_-_72151314 2.018 NM_018414
ST6GALNAC1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr20_-_55533544 1.961 NM_080618
CTCFL
CCCTC-binding factor (zinc finger protein)-like
chr12_+_53241365 1.872 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr3_-_197549588 1.855 TM4SF19
transmembrane 4 L six family member 19
chrX_+_48265107 1.668 NM_006579
EBP
emopamil binding protein (sterol isomerase)
chr19_-_54958326 1.566 NM_021733
TSKS
testis-specific serine kinase substrate
chr1_+_26517032 1.560 CD52
CD52 molecule
chr12_-_123914219 1.526 SCARB1
scavenger receptor class B, member 1
chr1_+_26516967 1.456 NM_001803
CD52
CD52 molecule
chr2_+_113648020 1.392 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr19_+_8180179 1.356 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr17_+_53769659 1.351 LOC100506779
hypothetical LOC100506779
chr3_-_197549640 1.325 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr1_-_154215558 1.324 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_+_26517045 1.321 CD52
CD52 molecule
chr22_-_21231421 1.320 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr6_+_31651319 1.268 NM_000594
TNF
tumor necrosis factor
chr11_+_5573906 1.255 NM_058166
TRIM6
tripartite motif containing 6
chr20_-_48741481 1.234


chr12_-_123914299 1.222 SCARB1
scavenger receptor class B, member 1
chr6_-_97391779 1.218 NM_001143957
NM_030784
GPR63

G protein-coupled receptor 63

chr12_-_123914375 1.160 NM_001082959
NM_005505
SCARB1

scavenger receptor class B, member 1

chr8_+_21972804 1.138 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr3_-_122862447 1.111 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr8_+_21972631 1.098 NM_001114138
NM_001978
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr3_+_39484073 1.066 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr2_+_113648036 1.060 PSD4
pleckstrin and Sec7 domain containing 4
chr19_-_13074513 1.054 LYL1
lymphoblastic leukemia derived sequence 1
chr1_-_26517342 1.040 NM_145345
UBXN11
UBX domain protein 11
chr1_+_20385164 1.030 NM_152376
UBXN10
UBX domain protein 10
chr20_+_44083667 1.014 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr1_+_144124547 1.004 NM_145277
NM_202004
NM_213652
NM_213653
HFE2



hemochromatosis type 2 (juvenile)



chr1_-_143706196 0.974 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_+_111215343 0.960 NM_001040033
CD53
CD53 molecule
chr1_+_203503214 0.932 TMCC2
transmembrane and coiled-coil domain family 2
chr22_-_25343959 0.929 NM_001887
CRYBB1
crystallin, beta B1
chr12_-_8110196 0.908 NM_004054
C3AR1
complement component 3a receptor 1
chr19_+_55844446 0.902 NM_001195076
LOC342918
hypothetical protein LOC342918
chr1_-_143706300 0.892 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr19_+_8023887 0.892 NM_005624
CCL25
chemokine (C-C motif) ligand 25
chr6_+_31662954 0.887 NM_001166538
NM_007161
NM_205840
LST1


leukocyte specific transcript 1


chr1_-_143706265 0.879 PDE4DIP
phosphodiesterase 4D interacting protein
chr12_+_7174230 0.867 NM_014718
CLSTN3
calsyntenin 3
chr22_+_21870293 0.858


chr19_-_13074669 0.856 LYL1
lymphoblastic leukemia derived sequence 1
chr4_-_73653331 0.852 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr16_-_1761504 0.840 NME3
non-metastatic cells 3, protein expressed in
chr6_-_133161318 0.824 NM_052831
C6orf192
chromosome 6 open reading frame 192
chr19_+_45797413 0.823 LTBP4
latent transforming growth factor beta binding protein 4
chr5_-_35083996 0.817 NM_031900
AGXT2
alanine--glyoxylate aminotransferase 2
chr14_-_23090606 0.799 NM_033400
ZFHX2
zinc finger homeobox 2
chr8_-_141536992 0.789 TRAPPC9
trafficking protein particle complex 9
chr6_-_31736488 0.786 NM_021184
C6orf47
chromosome 6 open reading frame 47
chr17_+_20712337 0.777


chr17_+_53769562 0.768 LOC100506779
hypothetical LOC100506779
chr11_+_5574440 0.761 NM_001003818
NM_001198644
NM_001198645
NM_001003819
TRIM6


TRIM6-TRIM34
tripartite motif containing 6


TRIM6-TRIM34 readthrough
chr1_+_205694237 0.757 NM_001006658
NM_001877
CR2

complement component (3d/Epstein Barr virus) receptor 2

chr14_-_22974707 0.749 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr1_+_160618143 0.746 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr16_+_31446703 0.744 NM_016633
AHSP
alpha hemoglobin stabilizing protein
chr12_-_8110268 0.735 C3AR1
complement component 3a receptor 1
chr10_+_35524835 0.726 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr19_-_53187151 0.706 NM_001128326
BSPH1
binder of sperm protein homolog 1
chr14_+_20306425 0.704 NM_022360
EDDM3B
epididymal protein 3B
chr19_-_13925192 0.701 NM_001146254
NM_001146255
PODNL1

podocan-like 1

chr1_-_159459814 0.698 APOA2
apolipoprotein A-II
chr16_-_1761710 0.695 NM_002513
NME3
non-metastatic cells 3, protein expressed in
chr19_-_63550712 0.695 A1BG
alpha-1-B glycoprotein
chr10_+_114125955 0.694 ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_+_40824486 0.694 NM_014209
ETV2
ets variant 2
chr19_+_51190535 0.690 CCDC61
coiled-coil domain containing 61
chr1_+_40930080 0.689 NFYC
nuclear transcription factor Y, gamma
chr1_-_159459999 0.688 NM_001643
APOA2
apolipoprotein A-II
chr1_+_202000906 0.687 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr1_-_26070330 0.678 NM_178422
PAQR7
progestin and adipoQ receptor family member VII
chr19_-_56537189 0.677 NM_001163922
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr4_+_22608252 0.664


chr10_+_114125927 0.662 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_-_37590910 0.661 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chr1_+_246682699 0.659 NM_001004136
OR2T2
olfactory receptor, family 2, subfamily T, member 2
chr1_+_40930015 0.657 NFYC
nuclear transcription factor Y, gamma
chr10_+_70745615 0.657 NM_033496
HK1
hexokinase 1
chr7_+_26298136 0.653 SNX10
sorting nexin 10
chr22_+_18388656 0.652 C22orf25
chromosome 22 open reading frame 25
chr6_+_31976754 0.650 NM_001178063
C2
complement component 2
chr22_+_34979062 0.648 NM_001136540
NM_001136541
NM_003661
NM_145343
APOL1



apolipoprotein L, 1



chr7_+_142670624 0.647 NM_001143679
NM_001143680
NM_001143681
NM_015917
GSTK1



glutathione S-transferase kappa 1



chr1_-_40930295 0.640 LOC100130557
hypothetical LOC100130557
chr17_+_71109734 0.636 MYO15B
myosin XVB pseudogene
chr6_-_29563657 0.635 NM_052967
MAS1L
MAS1 oncogene-like
chr22_+_34979118 0.629 APOL1
apolipoprotein L, 1
chr1_+_40929979 0.626 NFYC
nuclear transcription factor Y, gamma
chr3_-_197023096 0.623 MUC4
mucin 4, cell surface associated
chr16_-_2330594 0.622 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr1_+_40930062 0.618 NFYC
nuclear transcription factor Y, gamma
chr3_-_180460372 0.612 NM_171829
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr19_-_40925151 0.608 NM_024660
TMEM149
transmembrane protein 149
chr22_+_28206180 0.607 NM_021076
NEFH
neurofilament, heavy polypeptide
chrX_-_152863251 0.601 NM_002910
RENBP
renin binding protein
chr6_-_29703725 0.601 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_+_63030099 0.596 NM_001142535
NM_001142536
NM_033101
LGALS12


lectin, galactoside-binding, soluble, 12


chr2_+_74635019 0.596 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr22_+_18388633 0.596 C22orf25
chromosome 22 open reading frame 25
chr15_+_80741876 0.594 LOC80154
hypothetical LOC80154
chr3_+_20056527 0.592 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr8_-_66863841 0.591 NM_002603
PDE7A
phosphodiesterase 7A
chr1_+_234625338 0.583 NM_080738
EDARADD
EDAR-associated death domain
chr22_-_49041786 0.583 MAPK12
mitogen-activated protein kinase 12
chr22_+_34126104 0.583 NM_006739
MCM5
minichromosome maintenance complex component 5
chr17_+_51183439 0.581 NM_001102402
PCTP
phosphatidylcholine transfer protein
chr16_-_83209185 0.580 COTL1
coactosin-like 1 (Dictyostelium)
chr1_+_40929936 0.578 NFYC
nuclear transcription factor Y, gamma
chr1_+_40930233 0.572 NM_001142590
NFYC
nuclear transcription factor Y, gamma
chr2_+_171381626 0.572 GAD1
glutamate decarboxylase 1 (brain, 67kDa)
chr1_+_40929973 0.569 NFYC
nuclear transcription factor Y, gamma
chr16_-_83209140 0.566 NM_021149
COTL1
coactosin-like 1 (Dictyostelium)
chr1_-_2115950 0.561 NM_182533
C1orf86
chromosome 1 open reading frame 86
chr11_-_56761250 0.546 NM_005161
APLNR
apelin receptor
chr10_+_35524060 0.545 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr9_-_91302707 0.544 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr3_+_44746101 0.544 NM_145044
ZNF501
zinc finger protein 501
chr8_-_141537035 0.541 NM_001160372
TRAPPC9
trafficking protein particle complex 9
chr1_-_155053124 0.537 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr6_-_50025115 0.537 NM_001166478
DEFB133
defensin, beta 133
chrX_-_151672985 0.534 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr1_+_40929993 0.531 NFYC
nuclear transcription factor Y, gamma
chr10_+_114126004 0.529 ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_40929957 0.523 NFYC
nuclear transcription factor Y, gamma
chr4_-_176970372 0.523 GPM6A
glycoprotein M6A
chr7_+_2248966 0.522 NM_198953
NM_198954
NUDT1

nudix (nucleoside diphosphate linked moiety X)-type motif 1

chr1_-_155052562 0.520 NM_001161443
SH2D2A
SH2 domain containing 2A
chr11_-_117600918 0.518 NM_001098526
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr6_+_44076281 0.518 NM_001171992
NM_153246
C6orf223

chromosome 6 open reading frame 223

chr19_-_56549853 0.510 NM_001014763
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr13_+_51334117 0.509 NM_031290
CCDC70
coiled-coil domain containing 70
chr17_+_7279485 0.502 NM_178518
TMEM102
transmembrane protein 102
chr7_+_100310658 0.500 SRRT
serrate RNA effector molecule homolog (Arabidopsis)
chr15_+_72861767 0.500 CSK
c-src tyrosine kinase
chr7_+_100310669 0.497 SRRT
serrate RNA effector molecule homolog (Arabidopsis)
chr1_-_120240635 0.494 NM_021794
ADAM30
ADAM metallopeptidase domain 30
chr14_-_20128721 0.487 NM_001024822
RNASE12
ribonuclease, RNase A family, 12 (non-active)
chr19_-_12853249 0.486 NM_001375
DNASE2
deoxyribonuclease II, lysosomal
chr2_+_201806410 0.486 NM_001080124
NM_001228
NM_033355
NM_033358
CASP8



caspase 8, apoptosis-related cysteine peptidase



chr17_-_36276987 0.484 NM_000223
KRT12
keratin 12
chr1_-_12599934 0.476 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr1_+_205736095 0.476 NM_000573
NM_000651
CR1

complement component (3b/4b) receptor 1 (Knops blood group)

chrX_-_1291526 0.470 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chrX_-_152139267 0.469 NM_004988
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr2_-_85490984 0.469 CAPG
capping protein (actin filament), gelsolin-like
chr17_+_51183412 0.464 PCTP
phosphatidylcholine transfer protein
chr16_-_56562512 0.463 NM_001135639
NM_001297
CNGB1

cyclic nucleotide gated channel beta 1

chr2_+_171381317 0.463 NM_000817
NM_013445
GAD1

glutamate decarboxylase 1 (brain, 67kDa)

chr12_+_56271259 0.463 PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr11_-_57038891 0.461 NM_001198810
SLC43A1
solute carrier family 43, member 1
chr7_-_100077072 0.459 NM_003227
TFR2
transferrin receptor 2
chr7_+_156128431 0.456 NM_001184997
RNF32
ring finger protein 32
chr12_+_6800950 0.454 NM_014449
NM_019858
GPR162

G protein-coupled receptor 162

chrX_+_128700605 0.451 NM_003399
XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr19_-_1966628 0.450 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr1_+_108765634 0.450 LOC400768
hypothetical LOC400768
chr13_+_113574925 0.449 NM_001143945
GAS6
growth arrest-specific 6
chrX_-_151688850 0.445 NM_005362
MAGEA3
melanoma antigen family A, 3
chr11_+_118259684 0.444 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr19_-_54636425 0.442 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr7_+_150065594 0.439 GIMAP5
GTPase, IMAP family member 5
chr7_-_99219639 0.438 NM_017460
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr19_+_54621499 0.437 NM_001195256
LOC645971
hypothetical protein LOC645971
chr7_+_100310607 0.436 NM_001128852
NM_001128853
NM_001128854
NM_015908
SRRT



serrate RNA effector molecule homolog (Arabidopsis)



chr5_+_133870175 0.435


chr2_-_85490997 0.434 NM_001747
CAPG
capping protein (actin filament), gelsolin-like
chr17_-_53651586 0.433 NM_017777
MKS1
Meckel syndrome, type 1
chr15_+_80741827 0.430 LOC80154
hypothetical LOC80154
chr9_+_130231027 0.430 CERCAM
cerebral endothelial cell adhesion molecule
chr11_-_56905178 0.429 NM_006093
PRG3
proteoglycan 3
chr16_-_2330712 0.428 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr20_+_3138055 0.428 NM_033453
NM_181493
ITPA

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

chr11_+_36274300 0.428 NM_001160167
PRR5L
proline rich 5 like
chr6_+_34590624 0.424 PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr1_-_246869181 0.421 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr7_+_26298018 0.413 NM_013322
SNX10
sorting nexin 10
chr11_+_66152309 0.413


chr17_+_42756140 0.413 C17orf57
chromosome 17 open reading frame 57
chr4_+_110968594 0.411 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr7_-_150352484 0.411 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr9_-_85761472 0.410 NM_032307
C9orf64
chromosome 9 open reading frame 64
chr17_-_7107229 0.408 NM_001185022
CLDN7
claudin 7
chr1_+_159462456 0.403 NM_032174
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr11_-_57039721 0.402 NM_003627
SLC43A1
solute carrier family 43, member 1
chr5_+_176492662 0.402 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr4_-_176970407 0.401 GPM6A
glycoprotein M6A
chr8_-_143996257 0.399 NM_000498
CYP11B2
cytochrome P450, family 11, subfamily B, polypeptide 2
chr2_-_17563186 0.397 NM_001099218
RAD51AP2
RAD51 associated protein 2
chr8_-_30826074 0.396 NM_031271
TEX15
testis expressed 15
chrX_+_23595534 0.394 PRDX4
peroxiredoxin 4
chr19_-_43919428 0.389 CAPN12
calpain 12
chr12_+_69148120 0.386


chr16_-_2330738 0.386 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.22 1.98e-02 GO:0005886 plasma membrane
1.21 3.39e-02 GO:0071944 cell periphery
1.31 4.61e-02 GO:0044459 plasma membrane part

Nothing significant found in function category.